Vitamin B5 Pantothenic acid, also called vitamin B5, is a water-soluble vitamin. Pantothenic acid is an essential nutrient. Animals require pantothenic acid in order to synthesize coenzyme-A, as well as to synthesize and metabolize proteins, carbohydrates, and fats. The anion is called pantothenate.
|Identification Infrared absorption 197K||Concordant with reference spectrum|
|Identification A solution (1 in 20) responds to the tests for calcium||Conform to USP30|
|Specific optical rotation||+25.0°~+27.5°|
|Alkalinity||No pink color is produced within 5 seconds|
|Loss on drying||Not more than 5.0%|
|Heavy metals||Not more than 0.002%|
|Ordinary impurities||Not more than 1.0%|
|Organic volatile impurities||Meet the requirements|
|Content of calcium||8.2~8.6%|
|Assay||Conform to USP30|
Pantothenic acid (vitamin B5) is an essential component of coenzyme A (CoA) and acyl carrier protein (ACP). In both CoA and ACP, a derivative of pantothenic acid, 4-phosphopantetheine, forms the active portion of the compound. COA is required for the chemical reactions that produce energy from carbohydrates, fats, and proteins and for the synthesis of essential fats, cholesterol, certain hormones, and the neurotransmitter acetylcholine. ACP is involved in the synthesis of fatty acids.
The principal functions of pantothenic acid are through CoA which is required for synthesis of essential fats, sterols, steroid hormones, melatonin, acetylcholine, and heme (a part of hemoglobin and many metabolic proteins).
Because of the instability of pantothenic acid, calcium pantothenate is widely used in the feed industry. The D form of pantothenate is with bioactivity.